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What happens if both parents are carriers?


What if both parents are SMA carriers?

What is the chance that my baby will have SMA?

Can I find out if my baby will have SMA?

Are the results of the tests definite?

Might others in my family be SMA carriers?

What if the amniocentesis or CVS results show that the baby does not have SMA?

What about future pregnancies?

If all tests show that the baby will have SMA, what are my options?

Carrier Testing home

What if both parents are SMA carriers?

The test results mean that you and your partner are both carriers of the abnormal SMA gene. This does not have any impact on your health. However, it means that you are at risk for having a baby with SMA. It is important to remember that the result you received does not mean that your baby will definitely have SMA.

If you and your partner have both been shown to be carriers of an abnormal SMA gene and have a child together, there is a 1-in-4 (25%) chance with each pregnancy that the child will have SMA. This is true even if you already have other children with or without SMA.

If SMA testing shows both parents are carriers, you might see a genetic counselor. There are several choices couples in your situation can make when thinking about possible future pregnancies. Some couples decided to:

Have prenatal testing, such as amniocentesis or CVS;
Accept this level of risk and have children without further testing;
Go through in vitro fertilization and test the embryos using Preimplantation Genetic Diagnosis (PGD);
Use donor sperm or donor eggs;
Not have other children.